Alternative approaches to overcome diastasis of damaged peripheral nerves. A review articleстатьяИсследовательская статья
Информация о цитировании статьи получена из
Scopus
Статья опубликована в журнале из списка Web of Science и/или Scopus
Дата последнего поиска статьи во внешних источниках: 29 июня 2022 г.
Аннотация:Damage of peripheral nerves is often accompanied by a primary or secondary diastasis (gap, spread) between the neural ends, thus complicating a standard manual nerve stitching by means of surgical threads. As based on analysis of published data, the effective techniques were proposed for surgical treatment of peripheral nerve damage accompanied by diastasis. Moreover, some limitations of autoneural plastics are clearly revealed. Therefore, overcoming of nerve diastasis following damage remains to be a strong need, especially when treating prolonged and multiple defects of nerve trunks. Usage of implants providing repair and junction of the damaged nerve seems to be an alternative option allowing end-to-end connection of the damaged nerve from its central to distal segment. Application of biocompatible and bio-degradable polymers as a neural prosthesis promotes more safe regeneration and does not require switching-off a donor nerve and its functions. Moreover, the options are improved which allow to influence rates and quality of the nerve damage repair.