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A Method of Obtaining Silver–Succinyl Chitosan Nanocomposites and their Antimicrobial Activityстатья
- Авторы: Aleksandrova V.A., Futoryanskaya A.M., Sadykova V.S.
- Журнал: Applied Biochemistry and Microbiology
- Том: 58
- Номер: 5
- Год издания: 2022
- Издательство: Maik Nauka/Interperiodica Publishing
- Местоположение издательства: Russian Federation
- Первая страница: 507
- Последняя страница: 512
- DOI: 10.1134/S0003683822050040
- Аннотация: To form silver nanoparticles by reduction from metal ions in the presence of a reducing agent,D-glucose, a water-soluble derivative of chitosan, succinyl-chitosan, was used as a polymer matrix at roomtemperature. The synthesis of silver nanoparticles can also be carried out without a reducing agent by thermalactivation of the system using an alkali (NaOH) as an accelerator. The presence of silver nanoparticles in theobtained colloidal solutions was judged by the appearance of an absorption band in the electron plasmon resonance spectra (max = 417 nm). It has been shown that the use of an additional component, polyethyleneoxide, in a macromolecular system makes it possible to obtain small silver nanoparticles (1–3 nm). Theresults of in vitro studies of the antimicrobial activity of the obtained colloidal solutions containing silvernanoparticles confirm that a decrease in the size of silver nanoparticles leads to an expansion of the spectrumof antibacterial activity of strains of gram-positive and gram-negative bacteria (B. subtilis ATCC 6633,S. aureus 209P, E. coli ATCC 25922) and to the manifestation of a pronounced antifungal action in relationto A. niger INA 00760.
- Добавил в систему: Садыкова Вера Сергеевна