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Toxicity and local irritation action of the biomedical cell product anti-HER2-CAR-T-NK upon multiply repeated administrationстатья
- Авторы: Goryacheva N.A., Rzhevskii D.I., Slashcheva G.A., Novikova N.I., Murashev A.N., Bondarenko D.A., Kiselevskii M.V., Chikileva I.O., Vlasenko R.Y.
- Журнал: Pharmaceutical Chemistry Journal
- Том: 55
- Номер: 12
- Год издания: 2022
- Издательство: Kluwer Academic/Plenum Publishers
- Местоположение издательства: United States
- Первая страница: 1276
- Последняя страница: 1281
- Аннотация: CAR-cell therapy is a promising new method of cancer treatment. The biomedical cell product Anti-HER2-CAR-T-NK cells has been found safe in a course of intraperitoneal injection at a human-equivalent therapeutic dose in male and female ICR mice. The obtained information can help in the future to form the basis of recommendations for preclinical studies of CAR-cell immunopreparations.
- Добавил в систему: Анисимова Наталья Юрьевна