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The aqueous humor proteome is intrinsically disorderedстатья
- Авторы: Djulbegovic M., Uversky V.N.
- Журнал: Biochemistry and Biophysics Reports
- Том: 29
- Год издания: 2022
- Первая страница: 101202
- Аннотация: •Our study demonstrated that intrinsic disorder is abundant in the aqueous humor.•The 749 aqueous proteins analyzed were enriched with disorder-promoting residues.•208 aqueous humor proteins were predicted to be highly intrinsically disordered.•Misregulation of IDPs may promote pathology in the aqueous humor.•IDPs in aqueous humor may serve as future targets for novel therapeutics.
- Добавил в систему: Уверский Владимир Николаевич