IDENTIFICATION OF POTENTIAL LUNG CANCER BIOMARKERS BY LIQUID CHROMATOGRAPHY TANDEM MASS SPECTROMETRY-BASED PROTEOMICS ANALYSIS OF SECRETOMES OF TWO LUNG CANCER CELL LINES

Shevchenko, V.E.; Kovalev, S.V.; Arnotskaya, N.E.; Kudryavtsev, I.A.

Информация о цитировании статьи получена из Web of Science, Scopus
Статья опубликована в журнале из списка Web of Science и/или Scopus
Дата последнего поиска статьи во внешних источниках: 24 марта 2017 г.

Авторы: Shevchenko V.E., Kovalev S.V., Arnotskaya N.E., Kudryavtsev I.A.
Журнал: European Journal of Mass Spectrometry
Том: 19
Номер: 5
Год издания: 2013
Издательство: IM Publications
Местоположение издательства: United Kingdom
Первая страница: 377
Последняя страница: 389
DOI: 10.1255/ejms.1247
Аннотация: A label-free nano-liquid chromatography tandem mass spectrometry proteomics analysis on the conditioned media (CM) of two lung cancer cell lines of different histological backgrounds to identify secreted or membrane-bound proteins as novel lung cancer biomarkers was performed. Five hundred and seventy seven proteins were identified and 38% of them were classified as extracellular or membrane-bound. For the search of potential biomarkers of lung cancer a series of selection criteria were proposed. We detected known or putative lung cancer markers. In addition, 40 novel proteins were identified, whose role as biomarkers of lung cancer should be explored further.
Добавил в систему: Ковалев Сергей Васильевич

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IDENTIFICATION OF POTENTIAL LUNG CANCER BIOMARKERS BY LIQUID CHROMATOGRAPHY TANDEM MASS SPECTROMETRY-BASED PROTEOMICS ANALYSIS OF SECRETOMES OF TWO LUNG CANCER CELL LINESстатья

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