Peptide-Containing Fraction from a Culture Medium of Fusarium Sambucinum: Composition and Biological Effectsстатья
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Web of Science
Статья опубликована в журнале из списка Web of Science и/или Scopus
Дата последнего поиска статьи во внешних источниках: 14 августа 2017 г.
Авторы:
Bogdanov V.V.,
Fatkulina E.F.,
Berezin B.B. ,
Ilyina A.P. ,
Yamskova V.P. ,
Yamskov and I.A
Журнал:
Applied Biochemistry and Microbiology
Том:
50
Номер:
2
Год издания:
2014
Издательство:
Maik Nauka/Interperiodica Publishing
Местоположение издательства:
Russian Federation
Первая страница:
177
Последняя страница:
183
DOI:
10.1134/S0003683814020069
Аннотация:
The culture fluid of the fungus Fusarium sambucinum was investigated for the presence of new peptide-containing bioregulators, previously identified in various mammalian and plant tissues. A fraction containing peptides with molecular weights from 1000 to 2000 Da, which exhibited specific membranotropic activity and a number of physical and chemical properties characteristic of this group of bioregulators, was obtained. The effects of this fraction on the model roller organotypic cultivation of liver tissue of the Pleurodeles waltl newt in vitro were investigated for the first time. This fraction caused the additional activation of pigmented liver cells of newt (analogues to Kupffer cells of the liver of mammals) and provided the maintenance of cell-cell adhesive interactions in tissues. The results show that a new group of peptide bioregulators was present in the culture medium of the fungus F. sambucinum. В© 2014 Pleiades Publishing, Inc.
Добавил в систему:
Березин Борис Борисович