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Evaluation of the influence of chromium and zinc ions on the collagenolysis process in solutions by the method of dynamic light scatteringстатья
- Авторы: Petrova A.V., Sidorova A.V., Sergeeva I.A., Petrova G.P.
- Журнал: Optics and Spectroscopy (English translation of Optika i Spektroskopiya)
- Том: 130
- Номер: 3
- Год издания: 2022
- Издательство: Optical Society of America
- Местоположение издательства: United States
- Первая страница: 663
- Последняя страница: 667
- DOI: 10.21883/EOS.2022.06.54701.23-22
- Аннотация: Using the method of dynamic light scattering, it was found that the rate of collagen cleavage under the influence of bacterial collagenase decreases by almost 4 times when protein molecules are doped with Cr3+ ions, and when the enzyme activator of Zn2+ ions is added, it increases by 1.3 times. Based on the experimental data, the reaction rate constants k1 were calculated. It was found that when collagen molecules are tanned with a chromium salt, it becomes more resistant to degradation in solutions containing zinc ions than in solutions with the addition of calcium ions, as we described in earlier works. Keywords: collagen type 1, bacterial collagenase, chromium chloride, zinc chloride, dynamic light scattering method, translational diffusion coefficient, hydrodynamic radius, reaction rate constant, collagenolysis, Clostridium histolyticum.
- Добавил в систему: Сергеева Ирина Александровна