Ways to increase the effectiveness of targeted therapy for metastatic colorectal cancer using prognostic biomarkers (Review)

Авторы: Niyozova Sh Kh, Kamishov S.V., Balenkov O.Yu
Журнал: Журнал теоретической и клинической медицины
Номер: 6
Год издания: 2022
Первая страница: 132
Последняя страница: 137
Аннотация: Despite the successes achieved in recent years in the treatment of patients with colorectal cancer (CRC) using new targeted drugs, the problem of finding the main predictive factors for the effectiveness of antitumor therapy remains an urgent problem. The review examines the role of proto-oncogenes involved in the EGFR signaling cascade in the development of CRC, which represent important molecular targets and can serve as independent predictive biomarkers in CRC, helping to identify patients who will benefit from treatment with targeted drugs. The ability to identify groups of patients who are more likely to respond to the proposed type of therapy than in the general population can significantly increase the effectiveness of therapy and improve long-term outcomes in patients with metastatic CRC.
Добавил в систему: Баленков Олег Юрьевич

	ИСТИНА	Войти в систему Регистрация
	ИСТИНА ИНХС РАН
	Главная Поиск Статистика О проекте Помощь

ИСТИНА