Аннотация:The longitudinal study, conducted in high and average performance level professionals (50 teachers and 52 grid complex operators), was aimed to analyze the role of effective professional functional state's self-regulation under long-term innovation stress (in teachers) and under the tension of personnel assessment (in operators). The research was based on the Spencers` (1993) conceptual statement that key competences allow to differentiate efficient professionals from professionals with the superior performance; the ability of effective self-regulation of a functional state can be considered as such key competence in teachers' and operators' work. The methods included: the job stress survey (JSS), the coping questionnaire (SACS), the checklist designed to get data about coping means during the working day, the questionnaires that allow to evaluate changes in mental representation of a current functional state. The results revealed: the most effective functional state's self-regulation has been found in groups of high level performance teachers and operators; long-term tense conditions of innovative organizational changes require adaptive coping means that strictly correspond with accepted organizational rules and professional norms; short-time tensed conditions demand rapid targeted means of self-regulation. These results allow to elaborate training programs targeted for both maintaining high level of work performance and development of effective coping behavior.