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LAMININ-24 FROM HUMAN PLACENTA IS A BETTER ADHESION AGENT FOR PRIMARY KERATINOCYTESстатья
Информация о цитировании статьи получена из
Web of Science,
Scopus
Статья опубликована в журнале из списка Web of Science и/или Scopus
Дата последнего поиска статьи во внешних источниках: 30 апреля 2017 г.
- Авторы: Gorelik J.V., Cherepanova O.A., Voronkina I.V., Diakonov I.A., Blinova M.I., Pinaev G.P.
- Журнал: Cell Biology International
- Том: 25
- Номер: 5
- Год издания: 2001
- Издательство: Academic Press
- Местоположение издательства: United States
- Первая страница: 395
- Последняя страница: 402
- DOI: 10.1006/cbir.2000.0642
- Аннотация: A comparison of the adhesion of human primary keratinocytes to laminin-1 from murine EHS sarcoma and laminin-2/4 from human placenta was carried out using two methods, cell adhesion to substrates covered with the laminin isoforms, and interaction of keratinocytes from suspension with latex beads coated with the proteins. Laminin-2/4 was considerably more potent as a promoter of attachment of primary human keratinocytes than laminin-1 (and fibronectin), with increased attachment of cells correlating well with the number of latex bead binding sites. Only small cells of diameter of less than 20 μm bound more than 5 beads. Staining of keratinocytes with involucrin antibodies confirmed the existence of an inverse relationship between laminin-2/4-coated bead binding and differentiation.
- Добавил в систему: Воронкина Ирина Владимировна