Аннотация:S u b j e ct. Innovative activity of enterprises in the real sector T o p i c . Evaluation of innovative activity in the regions. G o a l . Analysis and evaluation of innovation activity in the regions of the Russian Federation. R e s u l t s . Certain aspects of innovative activity are analyzed. An assessment is made of the factors influencing the innovative activity of the regions of the Central Federal District. Leading and lagging regions in this aspect are identified. Important problems in the development of innovative activity are considered and trends of changes for the coming years are predicted.