PREPARATION OF N-PHENYL-SUBSTITUTED QUINOLINIUM DERIVATIVES LABELED WITH TRITIUM BY CHEMONUCLEAR SYNTHESISстатья
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Дата последнего поиска статьи во внешних источниках: 18 июля 2013 г.
Аннотация:A chemonuclear method of synthesis is proposed for obtaining difficultly available phenyl-substituted derivatives of quinoline labeled with tritium. The ion-molecule reaction of free phenyl cations, generated on beta-decay of tritium, with the nucleophilic centers of heterocyclic compounds is the basis of the synthesis. The onium derivatives synthesized possess significant inhibitory antimicrobial activity and are promising for a detailed study of the reaction mechanisms and metabolic processes using radioactive indicators.