Аннотация:Today the problem of reparation of damaged or lost human bone tissue is one of the most acute. IT is known, that the materials based on hydroxylapatite (Ca10(PO4)6(OH)2) are widely implemented for medical purposes, since their chemical composition is close to the non-organic constituent of human bone tissue. Unfortunately, some problems exist (low speed of resorption, weak resistance to propagation of cracks in case of ceramics), which limit implementation of the above materials in medicine. The present paper sets forth the method of chemical modification of hydroxylapatite by substitution of phosphate groups with sulphate ions, thus offering updated solubility of materials and sintering ability of powdered samples.