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Laser speckle contrast imaging of cerebral blood flow during carotid artery clampingстатья Тезисы
- Авторы: Stavtsev Dmitry D., Kozlov Igor O., Konovalov Anton N., Grebenev Fyodor V., Piavchenko Gennadii A., Gerasimenko Alexander Y., Telyshev Dmitry V., Meglinski Igor V., Kuznetsov Sergey L.
- Сборник: Diffuse Optical Spectroscopy and Imaging IX
- Серия: Proc. SPIE 12628, 126281S (8 December 2023)
- Год издания: 2023
- Место издания: SPIE
- DOI: 10.1117/12.2670756
- Аннотация: AbstractIn neurosurgical operations, such as cerebral aneurysm clipping, bypass surgery and arteriovenous malformations, monitoring of cerebral blood flow is critically important. Currently, surgeons do not have real-time noninvasive methods for intraoperative visualization of cerebral blood flow. Laser speckle contrast imaging (LSCI), widely used in the diagnosis of blood flow, may be promising for solving this problem. In the present study, the LSCI was demonstrated for the evaluation of acute cerebral blood flow abnormalities in laboratory animals. To visualize cerebral blood flow, the rats underwent cranial trepanation. The disruption of cerebral blood circulation was simulated by clamping both common carotid arteries through the neck approach. A specially designed LSCI system was used to assess blood flow. A distinct reduction in blood flow in the cerebral cortex after carotid artery clipping was shown, which lasted for 10 min continuously. At the same time, a more intensive blood flow decrease was observed in the right hemisphere, which can be related to the blood supply of the left hemisphere through the circle of Willis. After the clips were removed, blood flow in both hemispheres was restored to a level higher than the initial level. The results obtained show the prospects of using LSCI for the control of acute disorders of cerebral blood flow during neurosurgical operations in real-time.© (2023) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.Citation Download CitationDmitry Stavtsev, Igor Kozlov, Anton Konovalov, Fyodor Grebenev, Gennadii Piavchenko, Alexander Gerasimenko, Dmitry Telyshev, Igor Meglinski, and Sergey Kuznetsov "Laser speckle contrast imaging of cerebral blood flow during carotid artery clamping", Proc. SPIE 12628, Diffuse Optical Spectroscopy and Imaging IX, 126281S (8 December 2023); https://doi.org/10.1117/12.2670756
- Добавил в систему: Коновалов Антон Николаевич