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Blood Cytokines of the Ovarian Vein Basin in Different Stages of Pelvic Varicose Veinsстатья
Информация о цитировании статьи получена из
Scopus
Статья опубликована в журнале из списка Web of Science и/или Scopus
Дата последнего поиска статьи во внешних источниках: 15 февраля 2024 г.
- Авторы: Darenskaya M.A., Semendyaev A.A., Stupin D.A., Kolesnikov S.I., Semenova N.V., Pesterev K.V., Kolesnikova L.I.
- Журнал: Bulletin of Experimental Biology and Medicine
- Том: 175
- Номер: 3
- Год издания: 2023
- Издательство: Springer Nature
- Местоположение издательства: Switzerland
- Первая страница: 311
- Последняя страница: 314
- DOI: 10.1007/s10517-023-05858-3
- Аннотация: We analyzed the blood concentration of pro- and anti-inflammatory cytokines in the ovarian vein basin area in women of the reproductive age with primary pelvic varices. Increase in the disease severity was accompanied by a significant increase in proinflammatory cytokines (TNFα, IL-1β, IL-2, IL-6, and IL-8) and the proinflammatory index (IL-6/IL-10), whereas anti-inflammatory cytokine production changed ambiguously (increase of IL-4 at stage I, decrease of IL-10 at stage II, significant decrease of IL-4 and IL-10 at stage III). Control of these changes in female patients should probably be an important component of treatment measures and prevention of morphofunctional disorders occurring at disease progression, in particular at stage III of the disease.
- Добавил в систему: Болдин Владимир Алексеевич