Use of bone marrow mesenchymal (stromal) stem cells in experimental ischemic stroke in ratsстатья
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Статья опубликована в журнале из списка Web of Science и/или Scopus
Дата последнего поиска статьи во внешних источниках: 1 июля 2014 г.
Авторы:
Skvortsova V.I.a ,
Gubskiy ,
L V.a. ,
Tairova ,
R T.a.,
Povarova ,
O V.b.,
Cheglakov,
I B.c.,
Holodenko,
R V.d.,
Holodenko,
I V.d.,
Yarygin ,
K N.d.,
Yarygin,
V N.a.
Журнал:
Bulletin of Experimental Biology and Medicine
Том:
145
Номер:
1
Год издания:
2008
Издательство:
Springer Nature
Местоположение издательства:
Switzerland
Первая страница:
122
Последняя страница:
128
DOI:
10.1007/s10517-008-0032-7
Аннотация:
The effects of human mesenchymal stem cells on neurological functions and behavioral reactions of animals and on damaged brain tissue were studied on the model of focal cerebral ischemia in rats. Homing and differentiation of transplanted mesenchymal stem cells were also studied. Significant regression of neurological disorders after cell transplantation was noted, no appreciable shifts were detected by magnetic resonance tomography. Homing of transplanted cells was detected mainly in the zone of focal ischemia. Some cells died, others exhibited signs of differentiation into neurons and glia. © Springer Science+Business Media, Inc. 2008.
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Поварова Оксана Викторовна