Self-Assembled Porphyrin Nanoparticles Interaction Analysis with Albumin by Dynamic Light Scattering

Krot, A.R.; Ladynin, A.I.; Sergeeva, I.A.

Статья опубликована в журнале из списка RSCI Web of Science

Информация о цитировании статьи получена из Scopus
Статья опубликована в журнале из списка Web of Science и/или Scopus
Дата последнего поиска статьи во внешних источниках: 17 июля 2024 г.

Авторы: Krot A.R., Ladynin A.I., Sergeeva I.A.
Журнал: Journal of Biomedical Photonics & Engineering
Том: 10
Номер: 2
Год издания: 2024
Издательство: Samara National Research University
Местоположение издательства: Samara
Первая страница: 020305-1
Последняя страница: 020305-10
DOI: 10.18287/jbpe24.10.020305
Аннотация: We herein introduce the study of self-assembled porphyrazinenanoparticles photosensitizers in aqueous solutions with and without apolyvinylpyrrolidone carrier, respectively. For the first time, distributions ofhydrodynamic radii for each of the samples separately were obtained, as wellas corresponding changes in distributions for multicomponent systems in thepresence of human serum albumin. For reliable interpretation of the obtaineddistributions, a statistical processing method adapted to biological sampleswas used. The study identified combinations of photosensitizer nanoparticlesthat could either efficiently interact with human transport proteins or,conversely, maintain their stability in their presence. Thus, the researchconducted via dynamic light scattering revealed the potential forfundamentally different passive delivery methods of these nanoparticles: bothwith and without interaction with the main transport protein of human blood.© 2024 Journal of Biomedical Photonics & Engineering.
Добавил в систему: Сергеева Ирина Александровна

	ИСТИНА	Войти в систему Регистрация
	ИСТИНА ИНХС РАН
	Главная Поиск Статистика О проекте Помощь

ИСТИНА

ИСТИНА ИНХС РАН

Self-Assembled Porphyrin Nanoparticles Interaction Analysis with Albumin by Dynamic Light Scatteringстатья

Прикрепленные файлы