Enamine-based synthesis of functionalized aminoalkyl compounds bearing 3-, 4- or 5-coordinated phosphorus

Авторы: Bubnov Yu N., Prishchenko A.A., Livantsov M.V., Novikova O.P., Livantsova L.I., Baranin S.V.
Журнал: Russian Chemical Bulletin
Том: 73
Номер: 7
Год издания: 2024
Издательство: Springer Nature
Местоположение издательства: Switzerland
Первая страница: 1953
Последняя страница: 1961
Номер статьи: 112.1008.2023
Аннотация: A convenient synthesis of functionalized aminoalkyl organophosphorus compounds bearing 3-, 4- or 5-coordinated phosphorus atom is based on readily available enamines and trivalent phosphorus acid esters. Radical addition of bis(trimethylsiloxy)phosphine to enamines proceeds regioselectively to give aminoalkylphosphonites, and their subsequent functionalization afords various derivatives of the target acids. The nucleophilic addition of hydrospirophosphorane to enamines also proceeds regioselectively to furnish α-aminoalkyl spirophosphoranes containing ﬁve-coordinated phosphorus atom. The resulting compounds are of interest as promising biologically active substances and water-soluble ligands.
Добавил в систему: Прищенко Андрей Анатольевич

	ИСТИНА	Войти в систему Регистрация
	ИСТИНА ИНХС РАН
	Главная Поиск Статистика О проекте Помощь

ИСТИНА