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Роль глюкокортикоидов и стресса в биорегуляции редокс-гомеостаза в развитии и при старении. Доклады МОИР: сборник статей секции геронтологиистатья
- Авторы: Гудошников В.И., Прохоров Л.Ю.
- Сборник: Доклады МОИП: сборник статей секции геронтологии 2024 год
- Год издания: 2024
- Место издания: Longevity Books Канада, Торонто
- Первая страница: 25
- Последняя страница: 33
- Аннотация: Presented mini-review discusses the evidence available in the literature about the ability of both glucocorticoids and stress to shift the balance between pro-oxidant and antioxidant factors in the direction towards oxidative stress. Besides, bibliographic data confirm the capacity of vitamins C and E, as well as some other antioxidants to prevent these effects of glucocorticoids and stress. Finally, world literature, especially during the last years, demonstrates the important role of pro-oxidant actions of stress and glucocorticoids both in aging and during perinatal development, in association with programming / imprinting phenomena in the frame of DOHaD (Developmental Origins of Health and Disease) concept. It is suggested that the employment of known and novel antioxidant agents may be quite useful for counteracting the adverse effects of glucocorticoids and stress.
- Добавил в систему: Прохоров Леонид Юрьевич