Diastereoselective Synthesis of γ-Amino Acids and Their Derivatives from Nitroethane via Intermediacy of 5, 6-Dihydro-4H-1, 2-oxazines Bearing the CH2CH (CO2Me) 2 Substituent at C3статья
Информация о цитировании статьи получена из
Web of Science,
Scopus
Статья опубликована в журнале из списка Web of Science и/или Scopus
Дата последнего поиска статьи во внешних источниках: 19 сентября 2017 г.
Аннотация:Stereoselective two-step reduction of available 2-[(5, 6-dihydro-4H-1, 2-oxazin-3-yl)
methyl] malonates provides an efficient route to derivatives of different γ-amino acids. The
mechanism and stereochemistry of the first step, reduction of the C= N bond with sodium
cyanoborohydride, is discussed.