The Application of Novel Electrochemical  Approach to Antioxidant Activity Assay  of Metal Porphyrins with Bulky  3,5-Diisobornyl-4-hydroxyphenyl Moieties

Авторы: Rocheva T., Tyurin V., Belykh D., Moiseeva А.A., Zhang J., Buravlev Е., Chukicheva I., Kutchin А., Milaeva E.
Журнал: American Journal of Electroanalytical Chemistry
Том: 5
Номер: 15
Год издания: 2014
Первая страница: 1028
Последняя страница: 1036
DOI: 10.4236/ajac.2014.515109
Аннотация: The complexes of biogenic metals (Zn2+ ,Cu2+ ,Co2+ ,Mn3+ ,Fe3+ ) based on meso-tetra(3,5-diisobornyl- 4-hydroxyphenyl)porphyrin 1 were synthesized. The electrochemical behavior of these compounds was studied using cyclic voltammetry (CV) and rotating disk electrode (RDE) techniques. The antioxidant activity of complexes was estimated by means of the electrochemical assay based on the hydrogen atom transfer reaction to the stable radical 2,2’-diphenyl-1-picrylhydrazyl (DPPH). The RDE method was applied for this process monitoring. It was shown that the efficiency of the metal complexes (Cu2+ ,Co2+ ,Mn2+ ,Ni2+ ,Fe3+ ) is practically the same order as that of free base porphyrin 1. However the Zn2+ complex demonstrates significantly higher antioxidant activity, and the stoichiometry of the reaction was determined as σ = 4. The results demonstrate that porphyrin macrocycle can directly affect the antioxidant properties of 2,6-diisobornylphenol.
Добавил в систему: Тюрин Владимир Юрьевич

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