Synthetic Utilization of Polynitroaromatic Compounds. 4. Synthesis of Nitro-free 4,6-Disubstituted-3-aminobenzothiophene Derivatives Based on 2,4,6-Trinitrobenzamideстатья
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Дата последнего поиска статьи во внешних источниках: 17 ноября 2014 г.
Аннотация:A convenient synthesis of nitro-free 4,6-disubstituted 3 aminobenzothiophenes, their S-oxides and S,S-dioxides based on the available 2,4,6-trinitrobenzamide has been developed. The synthesis entails stepwise nucleophilic substitution of all nitro groups in the starting compound by S-, N-, and O-nucleophiles followed by Thorpe-Ziegler cyclization.