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Nanoscale organization of ionic liquids and their interaction with peptides probed by 13C NMR spectroscopyстатья
Информация о цитировании статьи получена из
Web of Science,
Scopus
Статья опубликована в журнале из списка Web of Science и/или Scopus
Дата последнего поиска статьи во внешних источниках: 12 января 2016 г.
- Авторы: Seitkalieva M.M., Grachev A.A., Egorova K.S., Ananikov V.P.
- Журнал: Tetrahedron
- Том: 70
- Год издания: 2014
- Издательство: Pergamon Press Ltd.
- Местоположение издательства: United Kingdom
- Первая страница: 6075
- Последняя страница: 6081
- DOI: 10.1016/j.tet.2014.02.025
- Аннотация: An NMR study of 10 l-alanine- and l-valine-containing peptides was carried out in the native [C2MIM][Cl], [C4MIM][Cl], [C6MIM][Cl], [C4MIM][BF4], [C4MIM][PF6], and [C4Py][BF4] ionic liquid media. A unique high sensitivity of the ionic liquid system to the nature of peptide and ability to tune solvent–solute interactions were observed in contrast to regular organic solvents. The l-valine peptides can be selectively dissolved in [C4MIM][Cl] and [C6MIM][Cl], whereas their solubility in [C2MIM][Cl] and other ionic liquids was dramatically lower. In spite of structural similarity between the amino acids, a distinct behavior was observed for the l-alanine peptides. Solvent–solute interactions with an ionic liquid impose significant changes, and NMR spectroscopy is a useful probe for the molecular-level and nanoscale organization of the studied systems. An even/odd effect of the number of amino acids in the peptide on molecular interactions in ionic liquids was observed. Enhancement of chemical properties of peptides in ionic liquids and application of ionic liquids in the separation of peptides are the areas of practical interest in the studied systems.
- Добавил в систему: Анаников Валентин Павлович