New Hyperbranched Sorbents for HPLC and Methods for Controlling their Separation AbilityстатьяИсследовательская статья
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Дата последнего поиска статьи во внешних источниках: 23 января 2026 г.
Аннотация:A series of silica-based sorbents with zwitterions in the functional layer attached via a spacer basedon 1,4-butanediol diglycidyl ether is synthesized. The effect of structural fragments of the stationary phase on the chromatographic properties in the hydrophilic chromatography mode is studied, and multifunctional capabilities for separating neutral polar, hydrophobic, and negatively charged compounds are demonstrated. Based on the revealed regularities, a sorbent with high separation capacity for carboxylic acids is created, which allows the separation of 13 organic acids in 25 min with a resolution of at least 1.0.