Laser-induced release of methylene blue from porous silicon nanoparticles for combined cancer therapy

Авторы: Bubnov А.А., Pokryshkin N.S., Timoshenko V.Yu
Журнал: Optical and Quantum Electronics
Том: 58
Номер: 2
Год издания: 2026
Издательство: Springer Nature
Местоположение издательства: Switzerland
Первая страница: 1
Последняя страница: 8
Номер статьи: 99
DOI: 10.1007/s11082-025-08606-1
Аннотация: Nanoparticles (NPs) of porous silicon (PSi) were loaded by Methylene blue (MB). The MB photoluminescence in the spectral region of 650–800 nm when excited by He-Ne laser at a wavelength of 633 nm. The polarization memory method was considered to make a decision about the state of MB (inside NPs or free MB in aqueous solution). The values of polarization for free MB and loaded MB were 6.2 and 9.5%, respectively. The MB release from the nanocontainer based on PSi NPs was found to be significantly promoted by nanosecond laser irradiation at 532 nm because of the local laser-induced heating of PSi NPs. The local heating was assessed by the Raman scattering method. The temperature of NPs increase was 30–50 degrees. This result allows us to control the release of MB from nanocontainers, which expands the possibilities of its use in combination cancer therapy.
Добавил в систему: Тимошенко Виктор Юрьевич

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