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A study of the properties of the C protein from skeletal and cardiac muscles of ground squirrel Citellus undulatus at different stages of the hibernationстатья
Информация о цитировании статьи получена из
Web of Science,
Scopus
Статья опубликована в журнале из списка Web of Science и/или Scopus
Дата последнего поиска статьи во внешних источниках: 3 февраля 2015 г.
- Авторы: Vikhlyantsev I.M., Alekseeva Y.A., Shpagina M.D., Udaltsov S.N., Podlubnaya Z.A.
- Журнал: Biophysics
- Том: 47
- Номер: 4
- Год издания: 2002
- Издательство: Maik Nauka/Interperiodica Publishing
- Местоположение издательства: Russian Federation
- Первая страница: 701
- Последняя страница: 705
- Аннотация: Changes in the molecular weight and functional properties of the C and X proteins from skeletal muscles and the C protein from the cardiac muscle of hibernating ground squirrels Citellus undulatus. at different stages of the hibernation were studied. A decrease in the molecular weight of the, C. protein from fast fibers of skeletal muscles of hibernating ground squirrels compared with awakening and active animals was revealed. The appearance of shorter molecules of the C protein upon hibernation was accompanied by a lowering of its capacity to enhance. the actin-activated ATPase activity of control myosin and by the inhibition of its Ca2+-sensitivity. No similar changes were observed for the skeletal X protein and the cardiac C protein. The influence of the skeletal C protein on the main functional properties of myosin allows one to draw a conclusion about its contribution to the inhibition of contractile activity of skeletal muscles upon hibernation. The physiological significance of the changes in the C protein upon hibernation is-discussed in connection with similar changes in some cardiomyopathies.
- Добавил в систему: Удальцов Сергей Николаевич