Determination of ceftriaxone by the fluorescence quenching of quantum dots using binding with polyethyleneimineстатья
Информация о цитировании статьи получена из
Web of Science,
Scopus
Статья опубликована в журнале из списка Web of Science и/или Scopus
Дата последнего поиска статьи во внешних источниках: 7 декабря 2017 г.
Аннотация:It is found that antibiotic ceftriaxone reacts with polyethyleneimine in aqueous solutions, probably, with the formation of a noncovalent molecular complex (complex I). The product of hydrolysis of complex I, when heated in an aqueous solution (product II), quenches the fluorescence of CdSe/CdS/ZnS core-shell-shell quantum dots, probably, because of the formation of free thiol groups. A possibility of ceftriaxone determination in aqueous solutions is demonstrated. The performance characteristics of the procedure using a spectrofluorimeter and a photocamera combined with a UV light-emitting diode are close to each other (cmin = 1 × 10–6 M, RSD = 10%). Na+, Ca2+, glucose, urea, uric acid, erythromycin, ciprofloxacin, and doxycycline produce no analytical signals under the conditions of ceftriaxone determination.