Аннотация:Investigations of the influence of anthropogenic pollution of spawning ponds on amphibian embryogenesis are held by us in natural populations of Common and Moor frogs (Rana temporaria and Rana arvalis) inhabiting the urban and suburb territory of Moscow. In the samples, fixed at the stage of hatching, the number of embryos with anomalies has been determined. We have shown that in Moscow city and outside the anomalies occur with approximately equal frequency. The most common anomalies are spinal curvature, slow time of development and skin defects. Anomaly spinal curvature is found in urban populations of 10% more than in suburb. This anomaly is lethal because such embryos are not able to swim normally at later stages of development. Histological studies showed that the cause of spinal curvature in dorsoventral direction is the somitogenesis defects. For the city, anomalies are more characteristic for the embryonic spatial structure, and for the suburb — for the skin layers. Differences between species were observed in the less common anomalies. For the common frog hydropsy is a characteristic anomaly, as well as a combination of deformation and skin defects and for the Moor frog — a combination of anomalies hydropsy and slow time of development. Significant interspecies differences in the frequency and nature of the anomalies were not found. However, interannual differences are more remarkable. This suggests that the frequency of occurrence of anomalies depends on the annual environmental situation.