|
ИСТИНА |
Войти в систему Регистрация |
ИСТИНА ИНХС РАН |
||
New superparamagnetic fluorescent Fe@C-C5ON2H10-Alexa Fluor 647 nanoparticles for biological applicationsстатья
Статья опубликована в журнале из списка RSCI Web of Science
Статья опубликована в журнале из перечня ВАКСтатья опубликована в журнале из списка Web of Science и/или Scopus
Дата последнего поиска статьи во внешних источниках: 23 сентября 2021 г.
- Авторы: Garanina A.S., Kireev I.I., Alieva I.B., Majouga A.G., Davydov V.A., Murugesan S., Khabashesku V.N., Agafonov V.N., Uzbekov R.E.
- Журнал: Наносистемы: физика, химия, математика
- Том: 9
- Номер: 1
- Год издания: 2018
- Издательство: Университет ИТМО
- Местоположение издательства: Санкт-Петербург
- Первая страница: 1
- Последняя страница: 3
- DOI: 10.17586/2220-8054-2018-9-1-120-122
- Аннотация: The structure and physical properties of superparamagnetic Fe@C nanoparticles (Fe@C NPs) as well as their uptake by living cells and behavior inside the cell were investigated. Magnetic capacity of Fe@C NPs was compared with Fe7C3@C NPs investigated in our previous work, and showed higher value of magnetic saturation, 75 emu.g−1(75 Am 2·kg−1), against 54emu.g−1(54 Am 2·kg−1) for Fe7C3@C. The surface of Fe@C NPs was alkylcarboxylated and further aminated for covalent linking to the molecules of fluorochrome Alexa Fluor 647. Fluorescent Fe@C-C5ON2H10-Alexa Fluor 647 NPs (Fe@C-AlexaNPs) were incubated with HT1080 human fibrosarcoma cells and investigated using fluorescent, confocal laser scanning and transmission electron microscopy. No toxic effect on the cell physiology was observed. In a magnetic field, the NPs became aligned along the magnetic lines inside the cells.
- Добавил в систему: Узбеков Рустем Эдуардович