Synthesis of novel α,β-unsaturated trifluoromethylketones with cyclobutene structure and their use for the preparation of bicyclic trifluoromethylated pyrrolesстатья
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Дата последнего поиска статьи во внешних источниках: 24 октября 2018 г.
Аннотация:A partial reduction of the strained β-pyrrolidino-α,β-unsaturated trifluoromethyl ketones with LiAlH4 gives the corresponding α,β-unsaturated trifluoromethyl ketones. Their interaction with 1-(methyleneamino)pyrrolidine in the presence of Mg(ClO4)2 proceeds through the several intermediate steps to afford trifluoromethylated pyrroles, condensed with substituted cylobutene fragments.