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We have demonstrated for the first time pacemaker-like automaticity in neonatal and juvenile rat SVC cardiac tissue that significantly reduces during postnatal maturation in rats. Adrenergic stimulations substantially enhance automaticity in neonatal and juvenile but not in adult SVC myocardium, probably via simultaneous α- and β-adrenoreceptor activation. This study is supported by Russian Science Foundation grant 14-15-00268.